Oct. 31st, 2002

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My office went all out today with the decorations and costumes--they even had a costume contest, and everyone who wore a costume got a lottery ticket. (I didn't win.) I wore the little witch dress that Adam bought me, slapped on some eyeshadow, and wore my quartz crystal pendant. I also brought in my deck of tarot cards featuring the Vertigo comic book universe (Neil Gaiman's Sandman, etc). Although I don't think I'll be reading them for anyone--most of the people here are Christians who might not understand my paganism. Luckily my library co-worker, Ray, does understand.

But that's what's been going on at work today.

Did I mention how comfortable polyester is? I never knew. My mom never let me wear the stuff. She preferred real fabrics to synthetic. Then again, she was a fashion illustrator for 20 years.

Cool...

Oct. 31st, 2002 01:15 pm
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Halloween: The Truth Is Out There

Science says there's no such thing as vampires or werewolves -- doesn't it? Come with us now as we take a look behind the veil of legend. The facts may be scarier than you think.

By Neil Osterweil
Reviewed By Michael Smith, MD
WebMD Feature

"From ghoulies and ghosties and long leggety beasties, and things that go bump in the night, Good Lord deliver us!," begs an old Scottish prayer. Fear can have a powerful grip on the unenlightened mind, but there is tantalizing evidence to suggest that legends of ghoulies and ghosties may be based in boring old reality.

Consider, for example, this description of the title character of Bram Stoker's Dracula:

"His eyebrows were very massive, almost meeting over the nose, and with bushy hair that seemed to curl in its own profusion. The mouth ... was fixed and rather cruel-looking, with peculiarly sharp white teeth; these protruded over the lips, whose remarkable ruddiness showed astonishing vitality in a man of his years ... The general effect was one of extraordinary pallor."

The bloodthirsty Count's physical features could have been caused, say some researchers, by a rare but very real disease. It's called porphyria cutanea tarda (PCT). PCT is the most common form of a genetic disease that results in abnormal pigments. And what part of your body needs these pigments? Your blood, of course -- specifically hemoglobin, the oxygen-carrying part of red blood cells.

People with PCT have skin that discolors and develops rashes and blisters when exposed to light. Those with more severe forms of the disease may have excessive hair growth on their face and hands (Dracula had hairs in the centers of his palms), gum degeneration (causing the teeth to appear large and protruding), and brain disorders. Some chemicals, including those found in garlic (a bane to vampires) can make their symptoms worse. Sometimes a person with PCT doesn't have enough red cells -- and needs repeated transfusions of blood.

"These symptoms, disease management strategies, and treatments are clearly reminiscent of characteristics typically associated with vampires and werewolves, and it is widely assumed that folkloric reports of such beasts may, in fact, be based on the suffering of unfortunate individuals afflicted with porphyria," writes plant geneticist Crispin B. Taylor, in the journal Plant Cell.

After the Flood

Many myths and legends probably have a basis in fact. For example, the ancient tale of a great flood, recorded in the Babylonian Epic of Gilgamesh around 2000 B.C. and later in the Biblical tale of Noah, probably refers to a cataclysmic deluge that occurred in the Middle East many millennia ago.

Similarly, ancient tales of witchcraft, vampires, werewolves, and other assorted phenomena may have come from superstitious misunderstanding of the natural world. People with epilepsy, for example, were thought to have been possessed by demons or to be under the spell of witches. Acromegaly, a chronic disease of the pituitary gland that causes over-secretion of growth hormone, results in enlargement and distortion of many parts of the skeleton, and may be responsible for stories of misshapen giants such as Goliath in the Bible and the boy-eating ogre in the tale Jack and the Beanstalk.

The ancients believed that the birth of a child with physical deformities was a sign of evil. The word "monster" itself comes from the Latin word "monstrum," meaning omen or portent.

But with the rise of evidence-based science in the 19th and 20th centuries, fear of the unknown began to wane, as exemplified in Dracula. The book represents "a conflict between a modern way of looking at the world and an ancient one," says Carol Senf, PhD, professor of literature, communication and culture at Georgia Institute of Technology in Atlanta. "I think that Stoker, two of whose three brothers were physicians, was interested in thinking about that. He's up on transfusions for example, and he's up on all kinds of scientific stuff."

Yet the death of Dracula -- with a stake right through his old undead ticker -- didn't end the legend of the vampire. It lives on in countless (no pun intended) movies, comic books, and even in the persona of the obsessive enumerator Count Von Count from Sesame Street.

Nor are vampires the only reality-based specters that still haunt our imaginations. Werewolves really exist -- or at least they do in the minds of people with the rare psychiatric disorder known as lycanthropy.

In the March 2000 issue of the Canadian Journal of Psychiatry, J. Arturo Silva, MD and Gregory B. Leong, MD describe the case of "Mr. A" who suffered from a case of partial lycanthropy -- the delusion that one is being transformed into a wolf.

"Mr. A is a 46-year-old male who experienced delusional episodes that lasted up to several hours. During these episodes, he had sensations of hair growth on his face, trunk, and arms. Occasionally, he became convinced that the hair growth was real. He also complained that he experienced structural facial malformations and lesions that took place within minutes and remained for hours. He thought these changes would make him appear to be a wolf, and avoided seeing his face or body whenever possible. However, he did not believe that he was a wolf. He denied that his mind was changing into a different mind or that he was a different person from his objective self."

Silva, who is a staff psychiatrist at the Veterans Affairs Medical Center in Palo Alto, Calif., tells WebMD that lycanthropy, "can be due to a hysteria or a psychosis -- in other words madness -- or it can be due to other kinds of illnesses, such as depression associated with a lot of self-deprecating thoughts. But often, once you start getting into a real belief system where somebody says 'I think I'm turning into a werewolf,' and he looks at his body and his hair, and the shape of his face changing -- once you get to that level it usually is a clear loss of contact with reality."

Silva says that lycanthropy is uncommon today -- probably because we've killed or banished most of the wolves to the remote wilderness and thus no longer live among them. However, people in other cultures in other parts of the world suffer from similar delusions, involving other types of animals, such as crocodiles or eagles.

Such transformations may seem to be the stuff of fantasy, but they still occur every year. If you don't believe it, just open your door this Halloween.

Originally published Oct. 29, 2001.
Medically reviewed Oct. 16, 2002.

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